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The intense inflammatory response seen in poison ivy is due to activity of the


A) cytotoxic T cells.
B) plasma cells.
C) delayed hypersensitivity cells.
D) macrophages.
E) mast cells.

F) C) and E)
G) A) and B)

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The MHC (major histocompatibility complex) class molecules


A) are only found on B cells.
B) are found in the nucleus of cells.
C) allow the immune system to respond to antigens inside cells.
D) are lipoproteins on cell surfaces.
E) do not attach to plasma membranes.

F) C) and E)
G) B) and C)

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All of the following lack lymphatic capillaries, except


A) the nervous system.
B) the bone marrow.
C) the epidermis.
D) cartilage.
E) skeletal muscle.

F) B) and C)
G) A) and D)

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A traditional method of providing temporary immunity for a person who is suspected of being infected (usually be an animal bite) with rabies is classified as


A) active natural immunity.
B) active artificial immunity.
C) passive natural immunity.
D) passive artificial immunity.
E) passive active immunity.

F) None of the above
G) B) and D)

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The effects of cell-mediated immunity are the result of activities of


A) B cells.
B) cytotoxic T cells.
C) macrophages.
D) dendritic cells.
E) helper T cells.

F) C) and D)
G) A) and D)

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Match the term with the appropriate description. -Peyer's patches


A) lipids that cause smooth muscle relaxation and vasodilation
B) lymph nodules aggregated in the small intestinal wall
C) rounded epithelial structures found in the medulla of thymus
D) areas of a lymph node where lymphocytes divide
E) a chemical released from mast cells that causes vasodilation

F) B) and D)
G) C) and D)

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Which of the following is NOT a function of the lymphatic system?


A) Defending from infection caused by microorganisms and other foreign substances.
B) Aiding in erythropoiesis of red blood cells.
C) Maintaining fluid balance by returning excess interstitial fluid to the blood.
D) Absorbing and transporting lipids from the digestive tract.

E) C) and D)
F) A) and B)

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What areas of an antigen are recognized by lymphocytes so that they can respond?


A) major histocompatibility complexes
B) antigenic determinants
C) T-cell receptors
D) epitopes
E) Both antigenic determinants and epitopes are correct.

F) B) and D)
G) C) and D)

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Adaptive immunity is stimulated by


A) antigens.
B) histamines.
C) antibodies.
D) complement.
E) plasma proteins.

F) C) and D)
G) A) and C)

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The two major types of phagocytic cells are


A) neutrophils and monocytes.
B) neutrophils and macrophages.
C) monocytes and macrophages.
D) lymphocytes and monocytes.
E) eosinophils and T cells.

F) A) and B)
G) B) and D)

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What structural feature of lymphatic vessels is responsible to forward movement of lymph?


A) over-lapping endothelial cells
B) valves
C) no basement membrane
D) thin walls

E) A) and D)
F) B) and C)

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The white pulp of the spleen


A) contains lymphocytes that can stimulate an immune response.
B) filters lymph as it flows through the spleen.
C) destroys defective red blood cells.
D) stimulates immune responses, filter lymph, and destroys defective red blood cells.

E) A) and C)
F) B) and C)

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Circulatory changes that occur in inflammation include


A) increased viscosity of the blood.
B) decreased vascular permeability.
C) increased vascular permeability.
D) decreased blood flow to the area.
E) vasoconstriction.

F) A) and E)
G) A) and D)

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Peyer patches are lymphatic nodules found in the


A) lymph nodes.
B) spleen and tonsils.
C) appendix and tonsils.
D) small intestine and appendix.

E) A) and B)
F) C) and D)

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Antibodies


A) play a large role in cell-mediated immunity.
B) are produced by both T and B cells.
C) are composed of four light and four heavy polypeptide chains.
D) are not specific, but act generally.
E) have a variable region that binds to a specific antigenic determinant.

F) A) and D)
G) All of the above

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Match the term or description to the type of hypersensitivity. -atopy


A) immediate hypersensitivity
B) delayed hypersensitivity

C) A) and B)
D) undefined

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Activation of the complement cascade via the alternative pathway involves the spontaneous activation of the complement protein _____________.


A) C1
B) C2
C) C4
D) C5
E) C3

F) A) and C)
G) B) and C)

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An individual develops a cold from a co-worker. This is an example of ______ immunity.


A) active artificial
B) passive natural
C) passive artificial
D) active natural

E) A) and B)
F) All of the above

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______ determines which B-cell is cloned in an antibody-mediated response.


A) The antibody
B) The antigen
C) A macrophage
D) Complement
E) A neutrophil

F) D) and E)
G) A) and B)

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Transplanted tissues and organs that contain _________ _________ are rejected by the body.


A) self-antigens
B) foreign antigens
C) foreign antibodies
D) self-antibodies
E) plasma proteins

F) A) and C)
G) All of the above

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